Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409821 | 0.94 | HDAC8 (0.36) | HDAC4HDAC8HDAC6 | |
| SCHEMBL4565697 | 0.79 | GRM4 (0.36) | SLC1A2SLC1A1 | |
| SCHEMBL4565810 | 0.79 | GRM4 (0.36) | SLC1A2SLC1A1 | |
| SCHEMBL2453547 | 0.74 | GRM4 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL4565617 | 0.74 | GRM4 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL4565712 | 0.74 | GRM4 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL25601715 | 0.66 | SLC1A2 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL31332648 | 0.66 | SLC1A2 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL6221971 | 0.66 | SLC1A2 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL9006136 | 0.65 | GRM4 (0.35) | SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |