Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4565712 | 1.00 | GRM4 (0.35) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL4565617 | 1.00 | GRM4 (0.35) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL4565697 | 0.93 | GRM4 (0.36) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL4565810 | 0.93 | GRM4 (0.36) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL8409821 | 0.80 | HDAC8 (0.36) | HSD11B1 | |
| SCHEMBL14536263 | 0.77 | HSD11B1 (0.36) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL25218266 | 0.77 | GRM4 (0.38) | GRM4CYP2C19LMNACYP1A2GRM2 | |
| SCHEMBL6142784 | 0.76 | LMNA (0.33) | CYP2C19LMNATSHRHSD11B1 | |
| SCHEMBL7130222 | 0.76 | LMNA (0.33) | CYP2C19LMNATSHRHSD11B1 | |
| SCHEMBL2832691 | 0.76 | LMNA (0.33) | CYP2C19LMNATSHRHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8017799-B2 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2011-09-13 | — | — | US | claimed |
| US-20090281349-A1 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2009-11-12 | — | — | US | claimed |
| US-8017799-B2 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2011-09-13 | — | — | US | disclosed |
| US-8017799-B2 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2011-09-13 | — | — | US | disclosed |
| US-20090281349-A1 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2009-11-12 | — | — | US | disclosed |
| US-20090281349-A1 | Hexahydrophthalate based compound and process for producing the same | NAN YA PLASTICS CORPORATION (TW) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281349-A1 | Hexahydrophthalate based compound and process for producing the same | RARA, DERA, ADH1A | GRM4 2790/4885CYP2C19 1991/4885LMNA 2531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.