Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | GRM8 | O00222 | 2/20 | 0.35 |
| ▸ | GRM6 | O15303 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | PLCB1 | Q9NQ66 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL895754 | 0.94 | GRM4 (0.34) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| SCHEMBL8452132 | 0.86 | SLC1A2 (0.38) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| SCHEMBL8018907 | 0.79 | NPSR1 (0.35) | SLC1A2SLC1A1 | |
| SCHEMBL8008305 | 0.74 | MAPT (0.40) | CYP2C19SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL988351 | 0.73 | GRM4 (0.38) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| SCHEMBL9018584 | 0.72 | GRM4 (0.41) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL25405452 | 0.71 | GRM4 (0.36) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| Hydrochloric Acid SCHEMBL3267782 | 0.71 | GRM4 (0.36) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| SCHEMBL8828098 | 0.71 | SLC6A4 (0.48) | GRM4CYP1A2CYP2C19GRM2GRM3 | |
| SCHEMBL4840309 | 0.71 | SLC6A4 (0.48) | GRM4CYP1A2CYP2C19GRM2GRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736561-A2 | Dihydroxy compound mixtures and polymers thereof | GENERAL ELECTRIC COMPANY (US) | 1996-10-09 | — | — | EP | disclosed |