Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 5/20 | 0.43 |
| ▸ | CA2 | P00918 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8054020 | 0.99 | LMNA (0.43) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL7801733 | 0.77 | LMNA (0.57) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL7951777 | 0.76 | LMNA (0.56) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL8006676 | 0.76 | LMNA (0.56) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL18633373 | 0.74 | LMNA (0.68) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL8026050 | 0.70 | MAPK1 (0.43) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL1031729 | 0.70 | LMNA (0.71) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL27396057 | 0.69 | CA1 (0.62) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL8595549 | 0.69 | MAPK1 (0.42) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL8024400 | 0.69 | MAPK1 (0.45) | LMNAALDH1A1MAPK1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060604-A | FOR RADIOTHERAPY TECHNIQUES, INCREASING TUMOR RADIOSENSITIVITY | FLORIDA STATE UNIVERSITY (US) | 2000-05-09 | — | — | US | disclosed |
| US-6057453-A | OXIDATION, FORMING RADIOSENSITIZING DIAMINES, REDUCTION | FLORIDA STATE UNIVERSITY (US) | 2000-05-02 | — | — | US | disclosed |