Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 5/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024400 | 0.95 | MAPK1 (0.45) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8595549 | 0.85 | MAPK1 (0.42) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL7803498 | 0.81 | MAPK1 (0.40) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8885703 | 0.80 | MAPK1 (0.44) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8887768 | 0.77 | MAPK1 (0.46) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL7803388 | 0.76 | LMNA (0.54) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8888171 | 0.74 | LMNA (0.56) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL13433889 | 0.72 | MAPK1 (0.55) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8054020 | 0.72 | LMNA (0.43) | MAPK1ATMLMNAALDH1A1THRB | |
| SCHEMBL8048622 | 0.70 | LMNA (0.43) | MAPK1ATMLMNAALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830357-A4 | RADIOSENSITIZING DIAMINES AND THEIR PHARMACEUTICAL PREPARATIONS | UNIV FLORIDA STATE (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0830357-A1 | RADIOSENSITIZING DIAMINES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996030365-A1 | RADIOSENSITIZING DIAMINES AND THEIR PHARMACEUTICAL PREPARATIONS | FLORIDA STATE UNIVERSITY (US) | 1996-10-03 | — | — | WO | disclosed |