SCHEMBL8048623

SCHEMBL8048623

C=CC[Si](C)(Br)CC=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15302446 0.80
SCHEMBL1289333 0.80
SCHEMBL52209 0.72
SCHEMBL232602 0.72 TSHR (0.38)
SCHEMBL231465 0.72
SCHEMBL236587 0.72
SCHEMBL235010 0.72 TSHR (0.32)
SCHEMBL233446 0.72
SCHEMBL278510 0.69
Water SCHEMBL28304970 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8791221-B2 Addition-curable metallosiloxane compound DAICEL CORPORATION (JP) 2014-07-29 US disclosed
EP-2650319-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND Daicel Corporation (JP) 2013-10-16 EP disclosed
US-20130267653-A1 ADDITION-CURABLE METALLOSILOXANE COMPOUND DAICEL CORPORATION (JP) 2013-10-10 US disclosed
EP-0729341-B1 HYDROPHILIZED DENTAL IMPRESSION COMPOUNDS ESPE DENTAL AG (DE) 2000-04-05 EP disclosed
US-5750589-A ETHER ADDUCT OR POLYMER HAVING CARBOSILANE GROUPS; STABILITY TO ANTISEPTIC BATHS THERA PATENT GMBH & CO. KG GESELLSCHAFT FUR (DE) 1998-05-12 US disclosed
EP-0729341-A1 HYDROPHILIZED DENTAL IMPRESSION COMPOUNDS THERA Patent GmbH & Co. KG Gesellschaft für industrielle Schutzrechte (DE) 1996-09-04 EP disclosed
WO-1996008230-A1 HYDROPHILIZED DENTAL IMPRESSION COMPOUNDS THERA PATENT GMBH & CO. KG GESELLSCHAFT FÜR INDUSTRIELLE SCHUTZRECHTE (DE) 1996-03-21 WO disclosed