SCHEMBL232602

SCHEMBL232602

C=CC[Si](Br)(CC=C)CC=C

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15301679 0.81 TSHR (0.32) TSHR
SCHEMBL15302008 0.81
SCHEMBL233446 0.77
SCHEMBL231465 0.77
SCHEMBL15301960 0.76 TSHR (0.35) TSHR
SCHEMBL15302095 0.76 TSHR (0.35) TSHR
SCHEMBL15303915 0.73 TSHR (0.40) TSHR
SCHEMBL15302078 0.73 TSHR (0.40) TSHR
SCHEMBL15302446 0.72
SCHEMBL234327 0.72 TSHR (0.35) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9399650-B2 Method for producing salts having monofluoro-tricyanoborate anions MERCK PATENT GMBH (DE) 2016-07-26 US claimed
US-20160130286-A1 METHOD FOR PRODUCING SALTS HAVING MONOFLUORO-TRICYANOBORATE ANIONS MERCK PATENT GMBH (DE) 2016-05-12 US claimed
WO-1993007879-A1 HETEROCYCLIC BISPHOSPHONIC ACID DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO claimed
JP-2233640-A None JP disclosed
EP-3392277-B1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR ALPHA-OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER USING SAME JAPAN POLYPROPYLENE CORP (JP) 2024-04-24 EP disclosed
US-10787468-B2 Acyl germanium photoinitiators and process for the preparation thereof IVOCLAR VIVADENT AG (LI) 2020-09-29 US disclosed
CN-108368192-B Method for producing solid catalyst component for alpha-olefin polymerization and method for producing alpha-olefin polymer using same 日本聚丙烯株式会社 2020-09-11 CN disclosed
US-20200087329-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof IVOCLAR VIVADENT AG (LI) 2020-03-19 US disclosed
US-10358526-B2 Moisture-curing polyether carbonate containing alkoxysilyl groups COVESTRO DEUTSCHLAND AG (DE) 2019-07-23 US disclosed
US-20180362673-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR ALPHA-OLEFIN POLYMERIZATION AND METHOD FOR PRODUCING ALPHA-OLEFIN POLYMER USING THE SAME JAPAN POLYPROPYLENE CORPORATION (JP) 2018-12-20 US disclosed
EP-3392277-A1 METHOD FOR PRODUCING SOLID CATALYST COMPONENT FOR -OLEFIN POLYMERIZATION, AND METHOD FOR PRODUCING -OLEFIN POLYMER USING SAME Japan Polypropylene Corporation (JP) 2018-10-24 EP disclosed
WO-1993014096-A1 PHOSPHONO DERIVATIVES OF AMINO ACIDS AS METALLOPROTEINASE INHIBITORS CELLTECH LIMITED (GB) 1993-07-22 WO disclosed
EP-0307221-B1 PROCESS FOR THE PREPARATION OF MACROLIDE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1993-06-02 EP disclosed
WO-1993007879-A1 HETEROCYCLIC BISPHOSPHONIC ACID DERIVATIVES AMERICAN HOME PRODUCTS CORPORATION (US) 1993-04-29 WO disclosed
US-5003096-A Alkylsilylaniline intermediates for herbicides THE DOW CHEMICAL COMPANY (US) 1991-03-26 US disclosed
JP-H02233640-A PRODUCTION OF ALPHA-BROMOACYL FLUORIDE AUSIMONT SRL 1990-09-17 JP disclosed
US-4910306-A Combining a sulfonyl halide with N-trialkylsilylaniline THE DOW CHEMICAL COMPANY (US) 1990-03-20 US disclosed
EP-0307221-A2 Process for the preparation of macrolide compounds AMERICAN CYANAMID COMPANY (US) 1989-03-15 EP disclosed
US-4703118-A Synthesis of 3-iodomethyl cephalosporins ELI LILLY AND COMPANY (US) 1987-10-27 US disclosed
US-3992422-A Process for the preparation of 21-halogeno-21-desoxy-17α-acyloxy-20-keto-pregnenes SCHERING CORPORATION (US) 1976-11-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160130286-A1 METHOD FOR PRODUCING SALTS HAVING MONOFLUORO-TRICYANOBORATE ANIONS SLC6A6, TBCB, CA6 TSHR 2937/4885
US-20200087329-A1 Acyl Germanium Photoinitiators And Process For The Preparation Thereof AGPAT5, AGPAT2, GLRA2 TSHR 2091/4885
US-10787468-B2 Acyl germanium photoinitiators and process for the preparation thereof AGPAT5, AGPAT2, GLRA2 TSHR 2091/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.