SCHEMBL8048683

SCHEMBL8048683

CC(C)CCCNCCCC(O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FDPS P14324 20/20 0.47
GGPS1 O95749 6/20 0.47
PDE3A Q14432 2/20 0.44
LMNA P02545 1/20 0.42
ADRB3 P13945 1/20 0.42
PDE4D Q08499 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10403160 0.93 FDPS (0.47) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL14284912 0.87 FDPS (0.59) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL24177186 0.84 FDPS (0.48) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL8049640 0.83 FDPS (0.61) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL24138222 0.80 FDPS (0.62) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL24668913 0.78 FDPS (0.59) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL12570894 0.77 FDPS (0.56) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL14179668 0.77 FDPS (0.52) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL4800069 0.74 FDPS (0.57) FDPSGGPS1PDE3ALMNAADRB3
SCHEMBL18330273 0.73 FDPS (0.47) FDPSGGPS1PDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0563096-B1 NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES LEIRAS OY (FI) 2000-05-03 EP claimed