Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 19/20 | 0.61 |
| ▸ | GGPS1 | O95749 | 8/20 | 0.61 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284912 | 0.96 | FDPS (0.59) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL12570894 | 0.85 | FDPS (0.56) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL8048683 | 0.83 | FDPS (0.47) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL15452862 | 0.82 | FDPS (0.76) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL10403160 | 0.80 | FDPS (0.47) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL10352125 | 0.80 | FDPS (0.47) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL9313278 | 0.79 | FDPS (0.77) | FDPSGGPS1PDE3ALMNAADRB3 | |
| SCHEMBL10486933 | 0.79 | GGPS1 (0.61) | FDPSGGPS1LMNA | |
| SCHEMBL24383912 | 0.78 | GGPS1 (0.39) | FDPSGGPS1LMNA | |
| SCHEMBL9313105 | 0.77 | FDPS (0.74) | FDPSGGPS1PDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563096-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| EP-0563096-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |
| US-4579720-A | USING HYDROXYMETHANE DIPHOSPHONIC ACID | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1986-04-01 | — | — | US | disclosed |
| US-4440646-A | HYDROXY OR HALOALKANEPHOSPHONATES | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1984-04-03 | — | — | US | disclosed |
| US-4188234-A | STABILIZATION OF VINYL POLYMERS, POLYPHOSPHONIC ACID CHELATING AGENT, PROTECTIVE COATINGS | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1980-02-12 | — | — | US | disclosed |
| US-4116990-A | OF NON-ALKALI METAL IONS WITH PHOSPHORUS CHELATING COMPOUND | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1978-09-26 | — | — | US | disclosed |
| US-4020091-A | TIN SALTS OF POLYPHOSPHONIC ACIDS | PLAINS CHEMICAL DEVELOPMENT CO. (US) | 1977-04-26 | — | — | US | disclosed |