SCHEMBL8048762

SCHEMBL8048762

CC(C)=CCc1nc(NO)c2[nH]cnc2n1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.50
CDK2 P24941 2/20 0.50
TSHR P16473 1/20 0.41
RECQL P46063 1/20 0.41
HIF1A Q16665 1/20 0.40
XDH P47989 1/20 0.40
MAPT P10636 1/20 0.40
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39
PDE4D Q08499 1/20 0.39
ADORA3 P0DMS8 1/20 0.36
GDA Q9Y2T3 1/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C19 P33261 1/20 0.36
CDK1 P06493 2/20 0.36
SYK P43405 1/20 0.36
LRRK2 Q5S007 1/20 0.35
HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL490904 0.81 PDPK1 (0.50) CYP1A2CDK2XDHGDACDK1
SCHEMBL30523416 0.75 CYP1A2 (0.65) CYP1A2CDK2TSHRRECQLHIF1A
SCHEMBL29959506 0.75 XDH (0.45) XDHMAPTADORA3CYP3A4CDK1
SCHEMBL7672747 0.75 XDH (0.45) XDHMAPTADORA3CYP3A4CDK1
SCHEMBL28878261 0.73 XDH (0.47) CYP1A2CDK2HIF1AXDHGDA
SCHEMBL19281406 0.73 CYP1A2 (0.46) CYP1A2CDK2HIF1AXDHMAPT
SCHEMBL30523393 0.73 CYP1A2 (0.62) CYP1A2CDK2TSHRRECQLHIF1A
SCHEMBL10910405 0.72 ALDH1A1 (0.45) CYP1A2CDK2TSHRRECQLCDK1
SCHEMBL1029880 0.72 XDH (0.45) CYP1A2CDK2HIF1AXDHPDE4A
SCHEMBL27678732 0.71 PDPK1 (0.42) CYP1A2CDK2GDACDK1MGMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0993776-A1 Composition for the treatment of cut tulip flowers Instituut voor Agrotechnologisch Onderzoek (ATO-DLO) (NL) 2000-04-19 EP disclosed