SCHEMBL8048914

SCHEMBL8048914

CCCNCCCCNCCC(O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.48
TSHR P16473 2/20 0.48
ALDH1A1 P00352 1/20 0.48
CYP2C19 P33261 2/20 0.40
CYP1A2 P05177 1/20 0.40
S1PR2 O95136 5/20 0.36
S1PR4 O95977 5/20 0.36
S1PR1 P21453 5/20 0.36
S1PR3 Q99500 5/20 0.36
S1PR5 Q9H228 1/20 0.36
MEN1 O00255 1/20 0.36
GLA P06280 1/20 0.36
KMT2A Q03164 1/20 0.36
HRH4 Q9H3N8 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
KDM1A O60341 2/20 0.33
ADH1B P00325 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4237376 0.93
Hydrochloric Acid SCHEMBL28202622 0.90 PAOX (0.37) PAOXTSHRALDH1A1ADH1BADH1A
SCHEMBL15973371 0.88 ALDH1A1 (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL745703 0.88 ALDH1A1 (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL7702557 0.88 ALDH1A1 (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL118049 0.88 ALDH1A1 (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL15109890 0.88 ALDH1A1 (0.59) TSHRALDH1A1S1PR2S1PR4S1PR1
SCHEMBL4230818 0.88 TSHR (0.50) PAOXTSHRALDH1A1CYP2C19CYP1A2
Hydrochloric Acid SCHEMBL6546522 0.86 ALDH1A1 (0.56) TSHRALDH1A1S1PR2S1PR4S1PR1
Hydrochloric Acid SCHEMBL283010 0.86 ALDH1A1 (0.56) TSHRALDH1A1S1PR2S1PR4S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6160022-A Chemical resection of pancreas UNIVERSITY OF FLORIDA (US) 2000-12-12 US disclosed