Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 known ✓ | O95136 | 5/20 | 0.47 |
| ▸ | S1PR4 known ✓ | O95977 | 5/20 | 0.47 |
| ▸ | S1PR1 known ✓ | P21453 | 5/20 | 0.47 |
| ▸ | S1PR3 known ✓ | Q99500 | 5/20 | 0.47 |
| ▸ | S1PR5 known ✓ | Q9H228 | 1/20 | 0.47 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.41 |
| ▸ | ADH1C | P00326 | 1/20 | 0.41 |
| ▸ | ADH1A | P07327 | 1/20 | 0.41 |
| ▸ | ADH4 | P08319 | 1/20 | 0.41 |
| ▸ | ADH7 | P40394 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5163421 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL6546522 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Hydrochloric Acid SCHEMBL9575896 | 1.00 | ALDH1A1 (0.56) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL15973371 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL15109890 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL745703 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL118049 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL7702557 | 0.98 | ALDH1A1 (0.59) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| Bromide SCHEMBL2858698 | 0.96 | ALDH1A1 (0.56) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL4230818 | 0.89 | TSHR (0.50) | ALDH1A1TSHRS1PR2S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12607948-B2 | Toner, toner production method, toner storage unit, image forming apparatus, and image forming method | RICOH COMPANY, LTD. (JP) | 2026-04-21 | — | — | US | disclosed |
| US-20230305412-A1 | TONER, TONER PRODUCTION METHOD, TONER STORAGE UNIT, IMAGE FORMING APPARATUS, AND IMAGE FORMING METHOD | RICOH COMPANY, LTD (JP) | 2023-09-28 | — | — | US | disclosed |
| CN-111321600-A | Fluoride-free waterproof processing finishing agent and application thereof | 京准化工技术(上海)有限公司 | 2020-06-23 | — | — | CN | disclosed |
| CN-111304919-A | Waterproof flame-retardant processing finishing agent | 京准化工技术(上海)有限公司 | 2020-06-19 | — | — | CN | disclosed |
| EP-2628053-B1 | TONER AND METHOD FOR PRODUCING THE SAME | RICOH CO LTD (JP) | 2019-06-26 | — | — | EP | disclosed |
| US-9857709-B2 | Toner and developer | RICOH COMPANY, LTD. (JP) | 2018-01-02 | — | — | US | disclosed |
| EP-2622415-B1 | TONER FOR DEVELOPING ELECTROSTATIC IMAGES AND DEVELOPER | RICOH CO LTD (JP) | 2017-12-20 | — | — | EP | disclosed |
| US-9523931-B2 | Toner, developer and image forming apparatus | RICOH COMPANY, LTD. (JP) | 2016-12-20 | — | — | US | disclosed |
| US-8911924-B2 | Toner and method for producing the same | RICOH COMPANY, LTD. (JP) | 2014-12-16 | — | — | US | disclosed |
| US-20140220485-A1 | TONER, DEVELOPER AND IMAGE FORMING APPARATUS | RICOH COMPANY, LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| EP-2428844-A1 | Electrophotographic toner, method of preparing said toner, toner supplying device and image forming apparatus | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2012-03-14 | — | — | EP | disclosed |
| US-20110200927-A1 | ELECTROPHOTOGRAPHIC TONER | SAMSUNG ELECTRONICS CO., LTD (KR) | 2011-08-18 | — | — | US | disclosed |
| US-7894751-B2 | Container for the storage of toner, container for the storage of developer and image-forming apparatus using these containers | FUJI XEROX CO., LTD. (JP) | 2011-02-22 | — | — | US | disclosed |
| US-20100239323-A1 | CONTAINER FOR THE STORAGE OF TONER, CONTAINER FOR THE STORAGE OF DEVELOPER AND IMAGE-FORMING APPARATUS USING THESE CONTAINERS | FUJI XEROX CO., LTD. (JP) | 2010-09-23 | — | — | US | disclosed |
| EP-2230553-A1 | Containers for the storage of toner, containers for the storage of developer and image-forming apparatuses using these containers | Fuji Xerox Co., Ltd. (JP) | 2010-09-22 | — | — | EP | disclosed |
| US-20100183970-A1 | ELECTROSTATIC IMAGE DEVELOPING CARRIER, ELECTROSTATIC IMAGE DEVELOPER, PROCESS CARTRIDGE, IMAGE FORMING METHOD, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20100183964-A1 | ELECTROSTATIC IMAGE DEVELOPING GREEN TONER, ELECTROSTATIC IMAGE DEVELOPER, ELECTROSTATIC IMAGE DEVELOPING TONER SET, ELECTROSTATIC IMAGE DEVELOPER SET AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2010-07-22 | — | — | US | disclosed |
| US-20090226834-A1 | ELECTROSTATIC IMAGE DEVELOPING TONER FOR PRESSURE FIXING, PRODUCTION METHOD OF THE SAME, ELECTROSTATIC IMAGE DEVELOPER, IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2009-09-10 | — | — | US | disclosed |
| US-6607864-B2 | Heating heating member that is in contact with a toner image to fix toner image onto a recording medium, wherein a surface of heating member or vicinity generates heat, and a toner forming the toner image contains a colorant and binder resin | FUJI XEROX CO., LTD. (JP) | 2003-08-19 | — | — | US | disclosed |
| US-20030027073-A1 | Image forming method | FUJI XEROX CO., LTD. (JP) | 2003-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12607948-B2 | Toner, toner production method, toner storage unit, image forming apparatus, and image forming method | VCP, ACTR2, COL1A1 | S1PR2 1995/4885S1PR4 1775/4885S1PR1 2257/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.