Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055900 | 0.80 | — | — | |
| SCHEMBL15025584 | 0.78 | — | — | |
| SCHEMBL16798783 | 0.74 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL313602 | 0.74 | AKR1B1 (0.39) | AKR1B1 | |
| SCHEMBL28085985 | 0.73 | AKR1B1 (0.31) | AKR1B1 | |
| SCHEMBL28275875 | 0.71 | — | — | |
| SCHEMBL5496629 | 0.71 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL18383123 | 0.71 | AKR1B1 (0.33) | AKR1B1 | |
| SCHEMBL16915296 | 0.69 | LMNA (0.40) | AKR1B1 | |
| SCHEMBL3645294 | 0.69 | LMNA (0.40) | AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0995430-A2 | Use of diacylolycerols for enhancing the barrier function of the skin | Beiersdorf Aktiengesellschaft (DE) | 2000-04-26 | — | — | EP | claimed |
| EP-0655907-B1 | USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES | UNIV BOSTON (US) | 1999-04-28 | — | — | EP | claimed |
| WO-1996009810-A1 | METHODS FOR ENHANCING MELANIN SYNTHESIS IN MELANOCYTES USING DIACYLGLYCEROLS AND USES THEREOF | TRUSTEES OF BOSTON UNIVERSITY (US) | 1996-04-04 | — | — | WO | claimed |
| EP-0995430-A2 | Use of diacylolycerols for enhancing the barrier function of the skin | Beiersdorf Aktiengesellschaft (DE) | 2000-04-26 | — | — | EP | disclosed |
| EP-0655907-B1 | USE OF DIACYLOLYCEROLS FOR INCREASING THE MELANIN CONTENT IN MELANOCYTES | UNIV BOSTON (US) | 1999-04-28 | — | — | EP | disclosed |
| US-5750091-A | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 1998-05-12 | — | — | US | disclosed |
| US-5700450-A | Methods for enhancing melanin synthesis in melanocytes using diacyglycerols and uses thereof | THE TRUSTEES OF BOSTON UNIVERSITY (US) | 1997-12-23 | — | — | US | disclosed |
| US-5352440-A | Methods for increasing melanin content in melanocytes using diacylglycerols and uses thereof | TRUSTEES OF BOSTON UNIVERSITY (US) | 1994-10-04 | — | — | US | disclosed |
| EP-0373195-A1 | COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. | TUFTS COLLEGE (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0373195-A4 | COMPOSITION FOR INCREASING MELANIN CONTENT OF MELANOCYTES IN-VIVO AND IN-VITRO AND METHODS FOR THE IN-VITRO USE THEREOF. | TUFTS COLLEGE (US) | 1990-05-14 | — | — | EP | disclosed |
| WO-1989009258-A1 | METHODS FOR INCREASING MELANIN CONTENT AND FOR INDUCING MELANOCYTE PROLIFERATION IN-VIVO AND IN-VITRO | TRUSTEES OF TUFTS COLLEGE (US) | 1989-10-05 | — | — | WO | disclosed |