Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8049679 | 0.99 | PRKCI (0.36) | PRKCISLC6A2CYP51A1SMN1; SMN2LIMK1 | |
| SCHEMBL8050768 | 0.84 | PRKCI (0.38) | PRKCISMN1; SMN2ALDH1A1ATM | |
| SCHEMBL8053626 | 0.80 | SLC6A2 (0.39) | SLC6A2CYP51A1SMN1; SMN2LIMK1 | |
| SCHEMBL4352573 | 0.79 | SLC6A2 (0.46) | SLC6A2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8051780 | 0.79 | SLC6A2 (0.39) | SLC6A2CYP51A1SMN1; SMN2LIMK1 | |
| Hydrochloric Acid SCHEMBL8053824 | 0.78 | SLC6A2 (0.45) | SLC6A2SMN1; SMN2ALDH1A1 | |
| SCHEMBL8439457 | 0.77 | SLC6A2 (0.35) | SLC6A2ALDH1A1 | |
| Fumaric Acid SCHEMBL8038874 | 0.76 | SLC6A2 (0.35) | PRKCISLC6A2ALDH1A1 | |
| Fumaric Acid SCHEMBL8038877 | 0.76 | SLC6A2 (0.35) | PRKCISLC6A2ALDH1A1 | |
| SCHEMBL8056707 | 0.75 | SLC6A2 (0.41) | SLC6A2CYP51A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |