Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.34 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8038855 | 0.99 | SLC6A2 (0.40) | SLC6A2CYP2A6ROCK1CRHR1GCGR | |
| SCHEMBL8039432 | 0.93 | SLC6A2 (0.37) | SLC6A2CYP2A6ROCK1CRHR1GCGR | |
| Hydrochloric Acid SCHEMBL9425165 | 0.92 | SLC6A2 (0.37) | SLC6A2CYP2A6ROCK1CRHR1GCGR | |
| SCHEMBL8050470 | 0.90 | ROCK1 (0.37) | SLC6A2CYP2A6ROCK1SREBF2NOS3 | |
| Hydrochloric Acid SCHEMBL8051640 | 0.89 | ROCK1 (0.36) | SLC6A2CYP2A6ROCK1SREBF2NOS3 | |
| SCHEMBL8054079 | 0.87 | CRHR1 (0.37) | SLC6A2CYP2A6ROCK1CRHR1GCGR | |
| SCHEMBL8053584 | 0.86 | SLC6A2 (0.35) | SLC6A2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL8052106 | 0.86 | CRHR1 (0.36) | SLC6A2CYP2A6ROCK1CRHR1GCGR | |
| SCHEMBL7337994 | 0.85 | SLC6A2 (0.34) | SLC6A2GCGRLMNAMAPT | |
| Hydrochloric Acid SCHEMBL8052007 | 0.85 | SLC6A2 (0.34) | SLC6A2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |