Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL8038877 | 0.91 | SLC6A2 (0.35) | PRKCIALDH1A1 | |
| Fumaric Acid SCHEMBL8038874 | 0.91 | SLC6A2 (0.35) | PRKCIALDH1A1 | |
| SCHEMBL8049504 | 0.84 | PRKCI (0.37) | PRKCISMN1; SMN2ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL8049679 | 0.83 | PRKCI (0.36) | PRKCISMN1; SMN2ALDH1A1ATM | |
| SCHEMBL8051650 | 0.81 | PRKCI (0.32) | PRKCISMN1; SMN2ALDH1A1ATM | |
| SCHEMBL8051666 | 0.80 | ALDH1A1 (0.37) | SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8051670 | 0.80 | LIMK1 (0.33) | PRKCISMN1; SMN2ALDH1A1ATM | |
| Hydrochloric Acid SCHEMBL8054087 | 0.79 | ALDH1A1 (0.36) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL8053422 | 0.76 | ROCK1 (0.35) | — | |
| Hydrochloric Acid SCHEMBL8053832 | 0.75 | ROCK1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |