Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 4/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8051427 | 0.99 | SLC6A2 (0.42) | SLC6A2PDGFRBEGFRKDRMAPT | |
| SCHEMBL8053584 | 0.84 | SLC6A2 (0.35) | SLC6A2PDGFRBMAPTALDH1A1HSD17B10 | |
| SCHEMBL7337994 | 0.83 | SLC6A2 (0.34) | SLC6A2MAPTALDH1A1BRAFPOLB | |
| Hydrochloric Acid SCHEMBL8052007 | 0.83 | SLC6A2 (0.34) | SLC6A2PDGFRBMAPTALDH1A1HSD17B10 | |
| SCHEMBL8056707 | 0.83 | SLC6A2 (0.41) | SLC6A2MAPTCRHR1KDM4E | |
| Hydrochloric Acid SCHEMBL7335002 | 0.82 | SLC6A2 (0.33) | SLC6A2BRAF | |
| Hydrochloric Acid SCHEMBL8038855 | 0.82 | SLC6A2 (0.40) | SLC6A2MAPTCRHR1KDM4E | |
| SCHEMBL8049772 | 0.80 | POLQ (0.36) | SLC6A2CYP11B1CYP11B2CYP19A1CRHR1 | |
| SCHEMBL4352573 | 0.80 | SLC6A2 (0.46) | SLC6A2MAPTALDH1A1 | |
| SCHEMBL8436369 | 0.80 | SLC6A2 (0.37) | SLC6A2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |