Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315596 | 0.76 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL30913766 | 0.73 | MAPT (0.39) | MAPK1 | |
| SCHEMBL30913780 | 0.70 | MAPK1 (0.42) | MAPK1 | |
| SCHEMBL15967486 | 0.70 | LPL (0.31) | — | |
| SCHEMBL5454232 | 0.68 | CYP3A4 (0.42) | MAPK1 | |
| SCHEMBL3598539 | 0.67 | KDM4E (0.34) | MAPK1 | |
| SCHEMBL7234998 | 0.66 | TDP1 (0.39) | MAPK1 | |
| SCHEMBL3598201 | 0.66 | ALOX5AP (0.33) | MAPK1 | |
| SCHEMBL23910519 | 0.65 | MAPK1 (0.44) | MAPK1 | |
| SCHEMBL1179212 | 0.65 | CA2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6083961-A | FOR PREVENTION AND/OR TREATMENT OF BRADYKININ OR ITS ANALOGUES MEDIATED DISEASES SUCH AS ALLERGY, INFLAMMATION, AUTOIMMUNE DISEASE, SHOCK, PAIN | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |