SCHEMBL8049657

SCHEMBL8049657

O=c1[nH]c(=O)c2sc3ccccc3c2[nH]1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
RAB9A P51151 1/20 0.56
TNKS O95271 4/20 0.54
TNKS2 Q9H2K2 4/20 0.54
ERCC5 P28715 1/20 0.54
FEN1 P39748 1/20 0.54
KDM4E B2RXH2 6/20 0.44
CA12 O43570 1/20 0.44
PARP1 P09874 1/20 0.44
CA9 Q16790 1/20 0.44
PIM1 P11309 1/20 0.43
PIM2 Q9P1W9 1/20 0.43
KRAS P01116 1/20 0.43
ALDH1A1 P00352 5/20 0.43
HTT P42858 3/20 0.43
NPSR1 Q6W5P4 2/20 0.43
HCRTR1 O43613 1/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4074785 0.80 MEN1 (0.62) MAPTMEN1KMT2ARAB9ATNKS
SCHEMBL18774624 0.78 MAPT (0.70) MAPTMEN1KMT2ARAB9ATNKS
SCHEMBL22007508 0.77 PIM1 (0.45) MAPTMEN1KMT2AKDM4EPARP1
SCHEMBL22006353 0.77 PIM1 (0.55) KDM4EPIM1PIM2
SCHEMBL22006355 0.75 DAO (0.42) KDM4ECA12PARP1CA9PIM1
SCHEMBL8689264 0.74 MEN1 (0.74) MAPTMEN1KMT2ARAB9ATNKS
SCHEMBL8049628 0.73 KRAS (0.43) KMT2ATNKSTNKS2KDM4EPARP1
SCHEMBL5729400 0.73 KDM4E (0.46) KMT2ARAB9AKDM4ECA12PARP1
SCHEMBL22006583 0.73 MAPK1 (0.40) KMT2ATNKSTNKS2KDM4EPARP1
SCHEMBL18647351 0.72 MEN1 (0.53) MAPTMEN1KMT2ARAB9ATNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6133275-A ALPHA 1 ADRENORECEPTOR ANTAGONISTS; TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER UROLOGICAL DISEASES E.G., BLADDER OUTLET OBSTRUCTION), NEUROGENIC BLADDER AND GYNECOLOGICAL SYNDROMES, E.G., DYSMENORRHEA; UTERINE MUSCLE RELAXANTS ABBOTT LABORATORIES (US) 2000-10-17 US claimed
WO-2023061998-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-04-20 WO disclosed
US-10361377-B2 Condensed cyclic compound and organic light emitting device including the same SAMSUNG SDI CO., LTD. (KR) 2019-07-23 US disclosed
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 US disclosed
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device SAMSUNG SDI CO., LTD. (KR) 2019-06-11 US disclosed
EP-3056498-B1 DIAZADIBENZOFURANE AND DIAZADIBENZOTHIOPHENE DERIVATIVES AND THEIR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG SDI CO LTD (KR) 2018-09-19 EP disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2018-01-25 US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2017-10-26 US disclosed
US-20160308143-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 US disclosed
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-10-20 US disclosed
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 US disclosed
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2016-08-18 US disclosed
EP-3056498-A1 DIAZADIBENZOFURANE AND DIAZADIBENZOTHIOPHENE DERIVATIVES AND THEIR USE IN ORGANIC OPTOELECTRONIC DEVICES Samsung SDI Co., Ltd. (KR) 2016-08-17 EP disclosed
WO-2015108301-A1 FUSED RING COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 삼성에스디아이 주식회사 2015-07-23 WO disclosed
WO-2015105316-A1 FUSED-RING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 삼성에스디아이 주식회사 2015-07-16 WO disclosed
WO-2015105315-A1 FUSED-RING COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 삼성에스디아이 주식회사 2015-07-16 WO disclosed
US-6133275-A ALPHA 1 ADRENORECEPTOR ANTAGONISTS; TREATING BENIGN PROSTATIC HYPERPLASIA AND OTHER UROLOGICAL DISEASES E.G., BLADDER OUTLET OBSTRUCTION), NEUROGENIC BLADDER AND GYNECOLOGICAL SYNDROMES, E.G., DYSMENORRHEA; UTERINE MUSCLE RELAXANTS ABBOTT LABORATORIES (US) 2000-10-17 US disclosed
EP-0808318-A1 TRICYCLIC SUBSTITUTED HEXAHYDROBENZ E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS Abbott Laboratories (US) 1997-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160308142-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MAPT 1162/4885MEN1 838/4885KMT2A 2013/4885
US-20160308143-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CRY2, CCNE2 MAPT 1250/4885MEN1 1122/4885KMT2A 1314/4885
US-10319921-B2 Composition for organic optoelectronic device and organic optoelectronic device and display device OR10J3, OR51E2, OXER1 MAPT 2759/4885MEN1 2391/4885KMT2A 4764/4885
US-20170309829-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC ELEMENT, ORGANIC OPTOELECTRONIC ELEMENT, AND DISPLAY DEVICE OCIAD2, OCIAD1, OR10J3 MAPT 2190/4885MEN1 2593/4885KMT2A 3837/4885
US-20160240791-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OXER1, OCIAD1 MAPT 2194/4885MEN1 3118/4885KMT2A 4272/4885
US-10361377-B2 Condensed cyclic compound and organic light emitting device including the same CRY1, CRY2, CCNE2 MAPT 1250/4885MEN1 1122/4885KMT2A 1314/4885
US-20180026205-A1 COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE AND ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OR10J3, OR51E2, OXER1 MAPT 2618/4885MEN1 2498/4885KMT2A 4763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.