Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP8 | P22894 | 3/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017605 | 1.00 | NAMPT (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8013654 | 1.00 | NAMPT (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL13783748 | 1.00 | NAMPT (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL15036653 | 0.79 | MAOB (0.39) | KMT2AMMP9MMP1MMP2MMP8 | |
| SCHEMBL8838933 | 0.77 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL1239662 | 0.77 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8279734 | 0.77 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL21916831 | 0.77 | P2RX7 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL8351029 | 0.77 | MEN1 (0.46) | NAMPTMEN1ALDH1A1KMT2AP2RX7 | |
| SCHEMBL18539300 | 0.77 | AURKA (0.43) | NAMPTMEN1ALDH1A1KMT2AP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991772-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | Biocatalytics, Inc. (US) | 2000-04-12 | — | — | EP | disclosed |
| US-5942644-A | Precursors for the production of chiral vicinal aminoalcohols | BIOCATALYTICS, INC. (US) | 1999-08-24 | — | — | US | disclosed |
| WO-1998054350-A1 | METHODS AND PRECURSORS FOR THE PRODUCTION OF CHIRAL VICINAL AMINOALCOHOLS | BIOCATALYTICS, INC. (US) | 1998-12-03 | — | — | WO | disclosed |