Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.37 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13783748 | 0.79 | NAMPT (0.43) | KMT2AMMP1MMP2MMP9MMP8 | |
| SCHEMBL8013654 | 0.79 | NAMPT (0.43) | KMT2AMMP1MMP2MMP9MMP8 | |
| SCHEMBL8017605 | 0.79 | NAMPT (0.43) | KMT2AMMP1MMP2MMP9MMP8 | |
| SCHEMBL8050161 | 0.79 | NAMPT (0.43) | KMT2AMMP1MMP2MMP9MMP8 | |
| SCHEMBL2578228 | 0.78 | SIGMAR1 (0.45) | MAOBMAOAOPRM1SIGMAR1 | |
| SCHEMBL2578214 | 0.78 | SIGMAR1 (0.45) | MAOBMAOAOPRM1SIGMAR1 | |
| SCHEMBL15705297 | 0.78 | SIGMAR1 (0.45) | MAOBMAOAOPRM1SIGMAR1 | |
| SCHEMBL19200270 | 0.77 | SIGMAR1 (0.39) | MAOBMAOAKMT2ASIGMAR1 | |
| SCHEMBL19960558 | 0.76 | PRCP (0.36) | PRCPKMT2AOPRM1SIGMAR1 | |
| SCHEMBL2464636 | 0.75 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2KMT2ASOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090696-A1 | CD4-MIMETIC INHIBITORS OF HIV-1 ENTRY AND METHODS OF USE THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2013-06-20 | — | — | WO | disclosed |