SCHEMBL8050174

SCHEMBL8050174

C=C(C)C(=O)OCC(CO)OC(=O)CCc1cc(-n2nc3ccc(Sc4ccccc4)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8040272 0.89 MAOB (0.32) MAOAMAOB
SCHEMBL8052028 0.88 MAOA (0.30) MAOAMAOB
SCHEMBL8384833 0.87 MAOB (0.31) MAOAMAOB
SCHEMBL8382964 0.86 MAOB (0.33) MAOAMAOB
SCHEMBL7148460 0.86
SCHEMBL9320497 0.83 MAOB (0.34) MAOAMAOB
SCHEMBL7522043 0.83
SCHEMBL8052031 0.82
SCHEMBL8050940 0.80 MAOB (0.39) MAOAMAOB
SCHEMBL9318475 0.80 MAOB (0.35) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5516914-A Compositions stabilized with 5-thio-substituted benzotriazole UV-absorbers CIBA-GEIGY CORPORATION (US) 1996-05-14 US claimed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP claimed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
EP-0572554-B1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA SC HOLDING AG (CH) 2000-05-10 EP disclosed
US-5516914-A Compositions stabilized with 5-thio-substituted benzotriazole UV-absorbers CIBA-GEIGY CORPORATION (US) 1996-05-14 US disclosed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US disclosed
US-5280124-A Having a phenol structure in position 2 CIBA-GEIGY CORPORATION (US) 1994-01-18 US disclosed
US-5278314-A N-Phenol-substituted benzotriazoles CIBA-GEIGY CORPORATION (US) 1994-01-11 US disclosed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP disclosed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP disclosed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO disclosed