SCHEMBL7148460

SCHEMBL7148460

C=C(C)C(=O)OCC(CO)OC(=O)CCc1cc(-n2nc3ccc(C(F)(F)F)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7522043 0.92
SCHEMBL6861415 0.90
SCHEMBL7532425 0.89
SCHEMBL8050174 0.86 MAOA (0.30)
SCHEMBL8052028 0.86 MAOA (0.30)
SCHEMBL3884142 0.83 GAA (0.32)
SCHEMBL7525894 0.81 ADRB2 (0.31)
SCHEMBL768820 0.81 GAA (0.41)
SCHEMBL29353898 0.81 GAA (0.41)
SCHEMBL7522045 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515051-B2 Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless CIBA SPECIALTY CHEMICALS CORPORATION 2003-02-04 US disclosed
US-6458872-B1 FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS CIBA SPECIALTY CHEMICALS CORPORATION 2002-10-01 US disclosed
US-20020099221-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-07-25 US disclosed
US-20020065341-A1 Benzotriazole UV absorbers having enhanced durability RAVICHANDRAN RAMANATHAN (US) 2002-05-30 US disclosed
US-6262151-B1 FOR AUTOMOTIVE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2001-07-17 US disclosed
US-6166218-A Benzotriazole UV absorbers having enhanced durability CIBA SPECIALTY CHEMICALS CORPORATION (US) 2000-12-26 US disclosed