Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.33 |
| ▸ | ABCC1 | P33527 | 3/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3858691 | 0.88 | ALDH1A1 (0.36) | HTT | |
| SCHEMBL29930396 | 0.88 | ALDH1A1 (0.36) | HTT | |
| SCHEMBL30963009 | 0.88 | ALDH1A1 (0.36) | HTT | |
| SCHEMBL30963008 | 0.88 | ALDH1A1 (0.36) | HTT | |
| SCHEMBL27481166 | 0.87 | SMN1; SMN2 (0.34) | PTGS2CHRM2CHRM1CACNA1ACACNA2D1 | |
| SCHEMBL29603281 | 0.84 | PSEN1 (0.38) | — | |
| SCHEMBL135175 | 0.84 | PSEN1 (0.38) | — | |
| SCHEMBL5834156 | 0.84 | CNR2 (0.37) | PTGS2ABCB1ABCC1 | |
| SCHEMBL21586964 | 0.81 | PTGS2 (0.37) | PTGS2ABCB1ABCC1HTT | |
| SCHEMBL8050308 | 0.79 | PTGS2 (0.33) | PTGS2ABCB1ABCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0572554-B1 | 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS | CIBA SC HOLDING AG (CH) | 2000-05-10 | — | — | EP | claimed |
| CN-100341859-C | Organic solvent-free preparation method of 2- (2-nitrophenylazo) phenols | CIBA SC HOLDING AG (CH) | 2007-10-10 | — | — | CN | disclosed |
| CN-1599777-A | Organic solvent-free process for the preparation of 2-(2-nitrophenylazo)phenols | CIBA SC HOLDING AG (CH) | 2005-03-23 | — | — | CN | disclosed |
| CN-1444568-A | Processes for preparation of benzotriazole UV absorbers | CIBA SC HOLDING AG (CH) | 2003-09-24 | — | — | CN | disclosed |