Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 20/20 | 0.45 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Olpadronic Acid SCHEMBL138988 | 0.84 | FDPS (0.58) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL12631211 | 0.82 | FDPS (0.49) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL232124 | 0.82 | FDPS (0.56) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL14044735 | 0.79 | FDPS (0.77) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL16091907 | 0.79 | FDPS (0.42) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8038129 | 0.79 | FDPS (0.37) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL5717996 | 0.76 | FDPS (0.55) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8048739 | 0.76 | FDPS (0.62) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| Olpadronic Acid SCHEMBL9581942 | 0.76 | FDPS (0.69) | FDPSGGPS1PDE3AAGTR1OPRM1 | |
| SCHEMBL8050464 | 0.74 | FDPS (0.68) | FDPSGGPS1PDE3ALMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563096-B1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 2000-05-03 | — | — | EP | disclosed |
| US-5438048-A | Used for treatment of disorders related to metabolism of calcium and other bivalent metals; treats bone cancer, urolithiasis, rheumatoid arthritis, bone infection and bone degradation | LEIRAS OY (FI) | 1995-08-01 | — | — | US | disclosed |
| WO-1992011267-A1 | NOVEL METHYLENEBISPHOSPHONIC ACID DERIVATIVES | LEIRAS OY (FI) | 1992-07-09 | — | — | WO | disclosed |