Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7523102 | 1.00 | TSHR (0.35) | TSHR | |
| SCHEMBL8930663 | 0.82 | TSHR (0.52) | TSHR | |
| SCHEMBL16756626 | 0.82 | — | — | |
| SCHEMBL8046387 | 0.77 | TSHR (0.37) | TSHR | |
| SCHEMBL9719308 | 0.60 | TSHR (0.62) | TSHR | |
| SCHEMBL8930654 | 0.59 | — | — | |
| SCHEMBL8930662 | 0.58 | TSHR (0.59) | TSHR | |
| SCHEMBL7136811 | 0.58 | — | — | |
| SCHEMBL7519328 | 0.58 | TSHR (1.00) | TSHR | |
| SCHEMBL9719293 | 0.58 | TSHR (0.52) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832054-B1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING AS (NO) | 2000-12-27 | — | — | EP | disclosed |
| US-6063360-A | USEFUL AS CONTRAST AGENT FOR OVERHAUSER MAGNETIC RESONACE IMAGING | NYCOMED IMAGING A/S (NO) | 2000-05-16 | — | — | US | disclosed |
| WO-1996039367-A1 | HETEROCYCLIC METHYL FREE RADICALS AS IMAGE ENHANCING AGENTS | NYCOMED IMAGING A/S (NO) | 1996-12-12 | — | — | WO | disclosed |
| US-5530140-A | Free radicals | NYCOMED IMAGING AS (NO) | 1996-06-25 | — | — | US | disclosed |