Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041914 | 0.90 | ALDH1A1 (0.33) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8042693 | 0.84 | ALDH1A1 (0.35) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8045604 | 0.84 | ALDH1A1 (0.34) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8044240 | 0.84 | KMT2A (0.35) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8042628 | 0.82 | ALDH1A1 (0.41) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8043561 | 0.82 | ALDH1A1 (0.52) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8042815 | 0.82 | ALDH1A1 (0.31) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8043610 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNATP53MAPTMAPK1 | |
| SCHEMBL8051376 | 0.79 | ALDH1A1 (0.45) | ALDH1A1LMNAMAPTMAPK1HTT | |
| SCHEMBL8052060 | 0.79 | MAPT (0.41) | ALDH1A1LMNATP53MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |