Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.50 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LGMN | Q99538 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5654750 | 1.00 | CYP3A4 (0.50) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| Hydrochloric Acid SCHEMBL6689154 | 0.98 | CYP3A4 (0.49) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| Hydrochloric Acid SCHEMBL3975530 | 0.98 | CYP3A4 (0.49) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| Hydrochloric Acid SCHEMBL6851464 | 0.98 | CYP3A4 (0.49) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| SCHEMBL276758 | 0.87 | LMNA (0.53) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| SCHEMBL296073 | 0.85 | CYP3A4 (0.49) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| SCHEMBL27475842 | 0.84 | CYP3A4 (0.50) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| SCHEMBL6647444 | 0.83 | AGXT (0.50) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| Hydrochloric Acid SCHEMBL5673046 | 0.83 | CYP3A4 (0.52) | CYP3A4CYP1A2AGXTLMNAKCNQ3 | |
| SCHEMBL783346 | 0.82 | ADRA2C (0.62) | AGXTALDH1A1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009050227-A1 | PYRIDAZINE DERIVATIVES FOR INHIBITING BETA AMYLOID PEPTIDE PRODUCTION | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |