Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 8/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26796194 | 0.75 | KDM4E (0.45) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL8553127 | 0.70 | MEN1 (0.39) | SMN1; SMN2LMNANPSR1MEN1KMT2A | |
| SCHEMBL2444846 | 0.70 | PKM (0.44) | SMN1; SMN2LMNANPSR1MEN1KMT2A | |
| SCHEMBL12599390 | 0.68 | HTT (0.63) | NPC1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL28346728 | 0.68 | NPC1 (0.56) | NPC1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL18620099 | 0.68 | HTT (0.62) | NPC1HTTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2443760 | 0.68 | PKM (0.41) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL11863078 | 0.67 | HTT (0.60) | NPC1HTTRAB9ASMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL8057997 | 0.66 | PKM (0.40) | NPC1RAB9ASMN1; SMN2LMNANPSR1 | |
| SCHEMBL3786921 | 0.66 | POLB (0.66) | NPC1HTTRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000226389-A | N-THIADIAZOLYLPYRAZOLECARBOXAMIDE DERIVATIVE AND INSECTICIDE AND ACARICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | MITSUBISHI CHEMICALS CORP | 2000-08-15 | — | — | JP | disclosed |