Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553290 | 0.75 | LRRK2 (0.49) | MEN1KMT2AMAPTSMN1; SMN2STIM1 | |
| SCHEMBL8553674 | 0.73 | P2RY1 (0.37) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8551683 | 0.72 | SMN1; SMN2 (0.41) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8551449 | 0.71 | GRM4 (0.55) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL12195699 | 0.70 | RIPK1 (0.36) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8556231 | 0.70 | RAB9A (0.51) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8050840 | 0.70 | NPC1 (0.46) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8554523 | 0.70 | GLA (0.42) | MEN1KMT2AMAPTSMN1; SMN2LMNA | |
| SCHEMBL8551758 | 0.69 | CASP3 (0.51) | MEN1KMT2AMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL8551900 | 0.69 | KDM4E (0.44) | MEN1KMT2AMAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | claimed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | claimed |
| EP-0566138-B1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO LTD (JP) | 1998-11-18 | — | — | EP | disclosed |
| EP-0566138-A1 | Amino thiazole derivatives and their use as fungicides | HODOGAYA CHEMICAL CO., LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |