SCHEMBL805126

SCHEMBL805126

CSCc1ccc(-c2ccc(C(=O)O)s2)s1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.47
LIG1 P18858 1/20 0.47
HPGD P15428 3/20 0.45
MEN1 O00255 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 1/20 0.45
KMT2A Q03164 1/20 0.45
DAO P14920 1/20 0.43
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 2/20 0.41
GAA P10253 1/20 0.41
HPGDS O60760 1/20 0.41
MKNK1 Q9BUB5 1/20 0.41
MKNK2 Q9HBH9 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10020291 0.98 PKM (0.46) PKMLIG1HPGDMEN1POLB
SCHEMBL29130661 0.90 PKM (0.53) PKMLIG1HPGDMEN1POLB
SCHEMBL13891701 0.81 HPGD (0.49) PKMLIG1HPGDMEN1POLB
SCHEMBL593023 0.78 MEN1 (0.65) HPGDMEN1POLBRAB9AKMT2A
SCHEMBL775264 0.77 MEN1 (0.49) HPGDMEN1POLBRAB9AKMT2A
SCHEMBL10020293 0.76 MEN1 (0.47) HPGDMEN1POLBRAB9AKMT2A
SCHEMBL2615881 0.75 MEN1 (0.63) HPGDMEN1POLBRAB9AKMT2A
Hydrochloric Acid SCHEMBL9447525 0.75 MEN1 (0.63) HPGDMEN1POLBRAB9AKMT2A
SCHEMBL2615879 0.75 MEN1 (0.63) HPGDMEN1POLBRAB9AKMT2A
SCHEMBL774287 0.75 MEN1 (0.46) HPGDMEN1POLBRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120067742-A1 LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP NATIONAL TAIWAN UNIVERSITY (TW) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120067742-A1 LINKER, IMPEDANCE BIOCHIP, AND METHOD OF QUANTITATIVELY DETECTING TARGET ANALYTE IN FLUID SAMPLE USING THE BIOCHIP EPCAM, CA13, CD44 PKM 3555/4885LIG1 1483/4885HPGD 2789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.