Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | DAO | P14920 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262044 | 0.88 | HPGD (0.56) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL593023 | 0.82 | MEN1 (0.65) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL775264 | 0.81 | MEN1 (0.49) | HPGDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL805126 | 0.81 | PKM (0.47) | HPGDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10020293 | 0.80 | MEN1 (0.47) | HPGDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL10020291 | 0.80 | PKM (0.46) | HPGDALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL2615881 | 0.80 | MEN1 (0.63) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| Hydrochloric Acid SCHEMBL9447525 | 0.80 | MEN1 (0.63) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL2615879 | 0.80 | MEN1 (0.63) | HPGDALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL13621245 | 0.79 | DPP4 (0.41) | HPGDALDH1A1MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383553-B2 | Dyes | MERCK PATENT GMBH (DE) | 2013-02-26 | — | — | US | disclosed |
| US-20090107552-A1 | Novel Dyes | MERCK KGAA (DE) | 2009-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090107552-A1 | Novel Dyes | CRY2, CRY1, HCCS | HPGD 2776/4885ALDH1A1 1538/4885TDP1 2231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.