Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.43 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697569 | 0.91 | FOLH1 (0.51) | FOLH1ALDH1A1 | |
| SCHEMBL4832572 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL4832582 | 0.82 | ALDH1A1 (0.48) | ALDH1A1CYP3A4LMNA | |
| SCHEMBL11165465 | 0.82 | ALDH1A1 (0.48) | FOLH1ALDH1A1 | |
| SCHEMBL4837028 | 0.82 | FOLH1 (0.50) | FOLH1ALDH1A1 | |
| SCHEMBL5146905 | 0.81 | ALDH1A1 (0.51) | FOLH1ALDH1A1KMT2ALMNA | |
| SCHEMBL9219335 | 0.76 | ALDH1A1 (0.53) | ALDH1A1CYP3A4KMT2ALMNA | |
| SCHEMBL5421388 | 0.76 | ALDH1A1 (0.53) | FOLH1ALDH1A1KMT2ALMNA | |
| SCHEMBL31422729 | 0.76 | ALDH1A1 (0.53) | FOLH1ALDH1A1KMT2ALMNA | |
| SCHEMBL2957718 | 0.75 | ALDH1A1 (0.51) | FOLH1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804413-B1 | NITROGEN MUSTARD PRODRUGS WITH NOVEL LIPOPHILIC PROTECTING GROUPS, AND PROCESSES FOR THEIR PRODUCTION | CANCER RES CAMPAIGN TECH (GB) | 2000-05-17 | — | — | EP | disclosed |