Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CPA3 | P15088 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8051476 | 0.91 | FOLH1 (0.43) | FOLH1ALDH1A1 | |
| SCHEMBL11165465 | 0.91 | ALDH1A1 (0.48) | FOLH1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL4837028 | 0.90 | FOLH1 (0.50) | FOLH1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL5146905 | 0.87 | ALDH1A1 (0.51) | FOLH1ALDH1A1SMN1; SMN2CPA3 | |
| SCHEMBL9219335 | 0.85 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL5421388 | 0.85 | ALDH1A1 (0.53) | FOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL31422729 | 0.85 | ALDH1A1 (0.53) | FOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2957718 | 0.84 | ALDH1A1 (0.51) | FOLH1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28773040 | 0.83 | FOLH1 (0.47) | FOLH1ALDH1A1SMN1; SMN2CPA3HTT | |
| SCHEMBL7087077 | 0.83 | FOLH1 (0.63) | FOLH1ALDH1A1CPA3HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0509643-A1 | Anti-cancer compounds | BTG INTERNATIONAL LIMITED (GB) | 1992-10-21 | — | — | EP | disclosed |