Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8693224 | 0.90 | MEN1 (0.42) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL16757270 | 0.85 | SLC6A2 (0.44) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27402701 | 0.85 | MEN1 (0.51) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9842210 | 0.84 | OPRD1 (0.38) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4275538 | 0.81 | MEN1 (0.44) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9842205 | 0.80 | OPRD1 (0.43) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL4153276 | 0.78 | MEN1 (0.53) | MEN1KMT2ASLC6A3OPRD1USP2 | |
| SCHEMBL4153281 | 0.78 | MEN1 (0.53) | MEN1KMT2ASLC6A3OPRD1USP2 | |
| SCHEMBL28346601 | 0.77 | TAAR1 (0.43) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9842320 | 0.77 | OPRD1 (0.36) | KMT2AOPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6130217-A | ANTITUMOR | PFIZER INC (US) | 2000-10-10 | — | — | US | disclosed |