Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842210 | 0.93 | OPRD1 (0.38) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL8051571 | 0.77 | MEN1 (0.47) | OPRD1OPRM1KMT2A | |
| SCHEMBL9842315 | 0.77 | OPRD1 (0.41) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL9842029 | 0.74 | CA1 (0.40) | — | |
| SCHEMBL9842287 | 0.74 | OPRD1 (0.39) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL9842280 | 0.72 | MITF (0.47) | — | |
| Hydrochloric Acid SCHEMBL8693224 | 0.72 | MEN1 (0.42) | OPRD1KMT2A | |
| SCHEMBL9842337 | 0.72 | OPRD1 (0.39) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL7427741 | 0.71 | ALDH1A1 (0.41) | OPRD1OPRM1OPRK1KMT2A | |
| SCHEMBL9842206 | 0.70 | OPRD1 (0.40) | OPRD1OPRM1OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0461264-A1 | ETHYNYLPHENYL DERIVATIVE, PRODUCTION THEREOF, AND REMEDY FOR DISEASES OF CIRCULATORY ORGANS CONTAINING THE SAME AS ACTIVE INGREDIENT | KAKEN PHARMACEUTICAL CO., LTD. (JP) | 1991-12-18 | — | — | EP | disclosed |