Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9066827 | 0.81 | HCRTR2 (0.39) | SMN1; SMN2TSHRALDH1A1TDP1 | |
| SCHEMBL805166 | 0.81 | TSHR (0.38) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL26938153 | 0.81 | TSHR (0.38) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL7083176 | 0.77 | TSHR (0.40) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL15683200 | 0.77 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL733109 | 0.76 | TSHR (0.50) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL285113 | 0.75 | TSHR (0.41) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL9066859 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2TSHRALDH1A1TDP1MAPK1 | |
| SCHEMBL28385789 | 0.74 | — | — | |
| SCHEMBL2554864 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2895570-A2 | SILOXANE ORGANIC HYBRID MATERIALS PROVIDING FLEXIBILITY TO EPOXY-BASED COATING COMPOSITONS | Momentive Performance Materials Inc. (US) | 2015-07-22 | — | — | EP | claimed |
| WO-2014042944-A2 | SILOXANE ORGANIC HYBRID MATERIALS PROVIDING FLEXIBILITY TO EPOXY-BASED COATING COMPOSITONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-03-20 | — | — | WO | claimed |
| EP-2895570-A2 | SILOXANE ORGANIC HYBRID MATERIALS PROVIDING FLEXIBILITY TO EPOXY-BASED COATING COMPOSITONS | Momentive Performance Materials Inc. (US) | 2015-07-22 | — | — | EP | disclosed |
| US-9000110-B2 | Fluoroalkyl group-containing n-substituted (meth)acrylamide compound, polymer thereof, and use thereof | AGC SEIMI CHEMICAL CO., LTD. (JP) | 2015-04-07 | — | — | US | disclosed |
| WO-2014042944-A2 | SILOXANE ORGANIC HYBRID MATERIALS PROVIDING FLEXIBILITY TO EPOXY-BASED COATING COMPOSITONS | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2014-03-20 | — | — | WO | disclosed |
| US-20120149860-A1 | FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF , AND USE THEREOF | AGC SEIMI CHEMICAL CO.,LTD. (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149860-A1 | FLUOROALKYL GROUP-CONTAINING N-SUBSTITUTED (METH)ACRYLAMIDE COMPOUND, POLYMER THEREOF , AND USE THEREOF | AFF2, AFF1, FRG1 | SMN1; SMN2 3754/4885TSHR 2065/4885ALDH1A1 3201/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.