Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 2/20 | 0.34 |
| ▸ | CHKA | P35790 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8054021 | 0.99 | GRM1 (0.34) | GRM1CHKACHRM5MAPTALDH1A1 | |
| SCHEMBL8054092 | 0.83 | CHKA (0.44) | GRM1CHKACHRM5MAPTLMNA | |
| SCHEMBL8052621 | 0.82 | POLQ (0.39) | CHKACHRM5 | |
| SCHEMBL8049764 | 0.82 | MAPK14 (0.33) | MAPTALDH1A1LMNAPOLBMAPK14 | |
| Hydrochloric Acid SCHEMBL8050418 | 0.82 | CHKA (0.43) | GRM1CHKACHRM5MAPTLMNA | |
| Hydrochloric Acid SCHEMBL8038783 | 0.81 | POLQ (0.39) | CHKACHRM5 | |
| Hydrochloric Acid SCHEMBL8050473 | 0.81 | MAPK14 (0.33) | MAPTALDH1A1LMNAPOLBMAPK14 | |
| SCHEMBL7337994 | 0.80 | SLC6A2 (0.34) | MAPTALDH1A1LMNAPOLBMAPK14 | |
| SCHEMBL8051657 | 0.80 | MPO (0.35) | MAPTALDH1A1LMNASMN1; SMN2ALOX5 | |
| Hydrochloric Acid SCHEMBL7335002 | 0.79 | SLC6A2 (0.33) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |