Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.40 |
| ▸ | STK16 | O75716 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | BMP2K | Q9NSY1 | 1/20 | 0.40 |
| ▸ | NLK | Q9UBE8 | 1/20 | 0.40 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8050875 | 0.99 | GAK (0.39) | GAKRIPK2STK16EGFRAAK1 | |
| SCHEMBL8052621 | 0.90 | POLQ (0.39) | GAKRIPK2STK16EGFRAAK1 | |
| Hydrochloric Acid SCHEMBL8038783 | 0.88 | POLQ (0.39) | GAKRIPK2STK16EGFRAAK1 | |
| SCHEMBL8056490 | 0.82 | POLQ (0.36) | GAKRIPK2STK16EGFRAAK1 | |
| SCHEMBL8038898 | 0.81 | POLQ (0.35) | AAK1POLQKIF11CHUKPIM1 | |
| Hydrochloric Acid SCHEMBL8050511 | 0.81 | POLQ (0.35) | POLQKIF11CHUKPIM1PIM2 | |
| Hydrochloric Acid SCHEMBL8049583 | 0.80 | POLQ (0.35) | POLQKIF11CHUKPIM1PIM2 | |
| SCHEMBL8039461 | 0.76 | MAPT (0.39) | MAPTMAPK1CHRM5CHKA | |
| SCHEMBL8440409 | 0.76 | CYP2A6 (0.43) | MAPTCHRM5CHKA | |
| Hydrochloric Acid SCHEMBL8039050 | 0.75 | MAPT (0.38) | MAPTMAPK1CHRM5CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |