Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CHKA | P35790 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8039050 | 0.98 | MAPT (0.38) | MAPTCHKACHRM5CYP2A6SLC6A4 | |
| SCHEMBL2742926 | 0.86 | MAPT (0.43) | MAPTCHKACYP2A6SLC6A4RAB9A | |
| SCHEMBL8440409 | 0.84 | CYP2A6 (0.43) | MAPTCHKACHRM5CYP2A6SMN1; SMN2 | |
| SCHEMBL8440253 | 0.84 | CHRM5 (0.38) | MAPTCHKACHRM5CYP2A6SMN1; SMN2 | |
| SCHEMBL8056316 | 0.80 | SLC6A2 (0.38) | MAPTCYP2A6SLC6A4GAASLC6A2 | |
| SCHEMBL8054092 | 0.79 | CHKA (0.44) | MAPTCHKACHRM5CYP2A6SLC6A2 | |
| SCHEMBL8051671 | 0.79 | GRM1 (0.34) | MAPTCHKACHRM5SMN1; SMN2GRM1 | |
| Hydrochloric Acid SCHEMBL8039091 | 0.79 | ALDH1A1 (0.40) | MAPTCYP2A6SLC6A4GAASLC6A2 | |
| SCHEMBL8435363 | 0.78 | CHKA (0.36) | MAPTCHKACHRM5SLC6A2SMN1; SMN2 | |
| SCHEMBL8440150 | 0.78 | CHRM5 (0.36) | MAPTCHKACHRM5RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022880-A | Substituted pyridylamino indoles | HOECHST MARION ROUSSEL, INC. (US) | 2000-02-08 | — | — | US | disclosed |
| US-5328920-A | Alleviating memory dysfunctions | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |