SCHEMBL8051967

SCHEMBL8051967

C/C(=C/c1ccc(O)cc1)C(=O)/C(C)=C/c1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.63
KDM4E B2RXH2 2/20 0.63
ESR1 P03372 4/20 0.54
ESR2 Q92731 4/20 0.54
PTGS2 P35354 3/20 0.48
NQO2 P16083 2/20 0.48
PTGS1 P23219 2/20 0.48
AKR1C3 P42330 1/20 0.48
ALDH5A1 P51649 1/20 0.46
ABAT P80404 1/20 0.46
CISD1 Q9NZ45 2/20 0.46
SLC16A3 O15427 1/20 0.46
CYP3A4 P08684 1/20 0.46
HPGD P15428 1/20 0.46
SLC16A1 P53985 1/20 0.46
GPR35 Q9HC97 1/20 0.46
TYR P14679 3/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
F3 P13726 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8051968 1.00 ALDH1A1 (0.63) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL15272115 0.86 ALDH1A1 (0.69) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL15272117 0.86 ALDH1A1 (0.69) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL83882 0.84 AKR1C3 (0.69) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL83883 0.84 AKR1C3 (0.69) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL5606972 0.83 AKR1C3 (0.67) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL5607656 0.83 AKR1C3 (0.67) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL5606699 0.83 AKR1C3 (0.67) ALDH1A1KDM4EESR1ESR2PTGS2
Potassium Ion SCHEMBL5607531 0.83 ALDH1A1 (0.59) ALDH1A1KDM4EESR1ESR2PTGS2
SCHEMBL5607625 0.83 AKR1C3 (0.67) ALDH1A1KDM4EESR1ESR2PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6043334-A USEFUL FOR PRODUCTION OF CROSSLINKED POLYCARBONATE RESINS; ELECTROPHOTOGRAPHIC PHOTORECEPTORS, WHICH HAVE PHOTOSENSITIVE LAYER CONTAINING CROSSLINKED POLYCARBONATE RESINS IDEMITSU KOSAN CO., LTD. (JP) 2000-03-28 US disclosed
EP-0866083-A1 POLYCARBONATE RESIN, CROSSLINKED POLYCARBONATE RESIN AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR IDEMITSU KOSAN COMPANY LIMITED (JP) 1998-09-23 EP disclosed