Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.52 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | NQO2 | P16083 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.45 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL83883 | 0.98 | AKR1C3 (0.69) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL83882 | 0.98 | AKR1C3 (0.69) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5606699 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607117 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607416 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607459 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607625 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607681 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| SCHEMBL5607656 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 | |
| Ammonia Solution, Strong SCHEMBL5607443 | 0.96 | AKR1C3 (0.67) | AKR1C3ALDH1A1KDM4ECISD1SLC16A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070142472-A1 | Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2007-06-21 | — | — | US | disclosed |
| EP-1687250-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | Takasago International Corporation (JP) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005051882-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-(4-HYDROXYPHENYL)PROPIONIC ACIDS | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070142472-A1 | Process for producing optically active 3-(4-hydroxyphenyl)proprionic acids | ALDH1A2, ALDH1A3, GRHPR | AKR1C3 16/4885ALDH1A1 5/4885KDM4E 3298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.