Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.35 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8043929 | 0.87 | MAPK8 (0.47) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8046591 | 0.84 | ALDH1A1 (0.39) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8042066 | 0.83 | RXRA (0.39) | MAPTALDH1A1HTTPKMKMT2A | |
| SCHEMBL8034225 | 0.83 | ALDH1A1 (0.38) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8044109 | 0.81 | MAPT (0.39) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8044381 | 0.80 | ALDH1A1 (0.36) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8043315 | 0.78 | ALDH1A1 (0.37) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8042606 | 0.78 | ALDH1A1 (0.37) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8044465 | 0.78 | ALDH1A1 (0.51) | MAPTALDH1A1HTTGAAPKM | |
| SCHEMBL8050613 | 0.78 | MAPT (0.46) | MAPTALDH1A1HTTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080772-A | 2-AMINOTHIAZOLE TRIAZOLE OR TETRAZOLE COMPOUND FOR REGULATING PROTEIN TYROSINE PHOSPHATASE ACTIVITY | SUGEN, INC. (US) | 2000-06-27 | — | — | US | disclosed |