SCHEMBL8052164

SCHEMBL8052164

OCCNc1nc(NCCO)nc(N2CCCCC2)n1

nearest known ligand 0.90

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GBA1 P04062 14/20 0.75
POLB P06746 1/20 0.75
SLC29A1 Q99808 3/20 0.66
MEN1 O00255 2/20 0.62
LMNA P02545 2/20 0.62
KMT2A Q03164 2/20 0.62
ALDH1A1 P00352 1/20 0.59
MAPT P10636 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14332238 0.88 GBA1 (0.65) GBA1POLBSLC29A1MEN1LMNA
SCHEMBL4132657 0.85 LMNA (0.76) GBA1POLBSLC29A1MEN1LMNA
SCHEMBL16884725 0.85 GBA1 (0.97) GBA1MEN1LMNAKMT2AALDH1A1
SCHEMBL8049805 0.83 GBA1 (0.70) GBA1POLBMEN1LMNAKMT2A
SCHEMBL21325586 0.80 GBA1 (0.56) GBA1POLBMEN1LMNAKMT2A
SCHEMBL7774642 0.79 LMNA (0.73) GBA1POLBMEN1LMNAKMT2A
SCHEMBL28769756 0.79 LMNA (0.67) GBA1POLBSLC29A1MEN1LMNA
SCHEMBL8611070 0.78 MEN1 (0.79) GBA1POLBMEN1LMNAKMT2A
SCHEMBL21325725 0.78 GBA1 (0.53) GBA1POLBSLC29A1MEN1LMNA
SCHEMBL9913727 0.77 LMNA (0.75) GBA1POLBMEN1LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6124381-A CURING ACCELERATOR IS A 2-((MONO- OR DI-ALKYL)AMINO, MORPHOLINO, PIPERIDINO, METHYL OR PHENYL)-4,6-SUBSTITUTED DIAMINO-1,3,5-TRIAZINE OF GIVEN FORMULA; POT LIFE, STORAGE STABILITY, AND WORKABILITY NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2000-09-26 US disclosed
EP-0834523-A1 EPOXY/ACID ANHYDRIDE COMPOSITION NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) 1998-04-08 EP disclosed