Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8804842 | 0.76 | L3MBTL1 (0.55) | L3MBTL1NPC1RAB9ATDP1LMNA | |
| SCHEMBL12152321 | 0.76 | L3MBTL1 (0.40) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21687919 | 0.72 | SRC (0.50) | L3MBTL1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9755853 | 0.72 | NPC1 (0.42) | L3MBTL1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4740644 | 0.72 | SRC (0.50) | L3MBTL1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL21687922 | 0.72 | SRC (0.50) | L3MBTL1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL9756551 | 0.69 | NPC1 (0.47) | L3MBTL1NPC1RAB9AKMT2ALMNA | |
| SCHEMBL1569023 | 0.69 | NPC1 (0.51) | L3MBTL1NPC1RAB9ALMNACYP2D6 | |
| SCHEMBL5344409 | 0.68 | KMT2A (0.48) | L3MBTL1RAB9AMEN1KMT2ATDP1 | |
| SCHEMBL13789642 | 0.67 | HDAC1 (0.57) | L3MBTL1NPC1RAB9AKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025350-A | C-4\" substituted macrolide antibiotics | PFIZER INC. (US) | 2000-02-15 | — | — | US | disclosed |