Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21687919 | 0.83 | SRC (0.50) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL21687922 | 0.83 | SRC (0.50) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL4740644 | 0.83 | SRC (0.50) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL1569023 | 0.79 | NPC1 (0.51) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL8804842 | 0.78 | L3MBTL1 (0.55) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL13789642 | 0.76 | HDAC1 (0.57) | NPC1RAB9AL3MBTL1LMNAPKM | |
| SCHEMBL1578734 | 0.76 | KMT2A (0.60) | NPC1RAB9AL3MBTL1LMNAPKM | |
| SCHEMBL8800354 | 0.75 | L3MBTL1 (0.44) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL1579063 | 0.75 | CTSD (0.63) | NPC1RAB9AL3MBTL1LMNACYP2D6 | |
| SCHEMBL9755853 | 0.74 | NPC1 (0.42) | NPC1RAB9AL3MBTL1LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0232075-B1 | INSECTICIDAL N'-SUBSTITUTED-N-ALKYLCARBONYL-N'-ACYL HYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-03-13 | — | — | EP | disclosed |
| EP-0234944-A1 | Insecticidal N'-substituted-N-acyl-N'-alkylcarbonylhydrazines | ROHM AND HAAS COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| EP-0232075-A1 | Insecticidal N'-substituted-N-alkylcarbonyl-N'-acyl hydrazines | ROHM AND HAAS COMPANY (US) | 1987-08-12 | — | — | EP | disclosed |