Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8052716 | 0.85 | NISCH (0.40) | NISCHSMN1; SMN2 | |
| SCHEMBL8044042 | 0.83 | NISCH (0.46) | NISCHSMN1; SMN2 | |
| SCHEMBL8045886 | 0.82 | NISCH (0.37) | NISCHSMN1; SMN2 | |
| SCHEMBL8045884 | 0.75 | NPC1 (0.44) | NISCHSMN1; SMN2 | |
| SCHEMBL9130147 | 0.74 | — | — | |
| SCHEMBL1338840 | 0.71 | ALDH1A1 (0.47) | NISCHDRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL10422186 | 0.68 | NISCH (0.41) | NISCHDRD2DRD4DRD3SMN1; SMN2 | |
| SCHEMBL8052225 | 0.67 | — | — | |
| SCHEMBL4054286 | 0.66 | SMN1; SMN2 (0.44) | NISCHSMN1; SMN2 | |
| SCHEMBL1548278 | 0.63 | ALDH1A1 (0.54) | NISCHSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661290-B1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD (JP) | 2000-04-26 | — | — | EP | disclosed |
| US-5446180-A | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0661290-A1 | Compounds containing 1-aza-3-oxa-4-silacyclohex-1-enyl groups, and tautomers of said compounds | DOW CORNING ASIA, Ltd. (JP) | 1995-07-05 | — | — | EP | disclosed |