Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8041339 | 0.86 | ALDH1A1 (0.43) | PKMPOLBMAPTMEN1KMT2A | |
| SCHEMBL30548266 | 0.77 | HSD17B10 (0.49) | HSD17B10PKMPOLBMAPTMEN1 | |
| SCHEMBL25251939 | 0.77 | HSD17B10 (0.49) | HSD17B10PKMPOLBMAPTMEN1 | |
| SCHEMBL7497270 | 0.70 | DYRK1A (0.33) | HSD17B10ALDH1A1HPGD | |
| SCHEMBL8052726 | 0.67 | KDM4E (0.30) | HSD17B10SMN1; SMN2HPGD | |
| SCHEMBL2398501 | 0.66 | GLA (0.52) | HSD17B10PKMPOLBMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7888843 | 0.66 | HIF1A (0.32) | HSD17B10MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL11657430 | 0.66 | HPGD (0.56) | HSD17B10MAPTSMN1; SMN2ALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7890565 | 0.66 | DYRK1A (0.38) | HSD17B10ALDH1A1HPGD | |
| SCHEMBL6699936 | 0.65 | GLS (0.71) | MAPTSMN1; SMN2CASP3L3MBTL1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0669336-B1 | NOVEL CEPHEM DERIVATIVES | MEIJI SEIKA CO (JP) | 2000-05-17 | — | — | EP | disclosed |
| US-5663162-A | BACTERICIDES AND ANTIBIOTICS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0669336-A1 | NOVEL CEPHEM DERIVATIVE | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-08-30 | — | — | EP | disclosed |