Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332593 | 0.84 | MEN1 (0.49) | KDM4EALDH1A1GAAPARP10IRAK4 | |
| SCHEMBL8044038 | 0.77 | ALDH1A1 (0.53) | KDM4EALDH1A1GAACYP3A4PARP10 | |
| SCHEMBL698749 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1GAACYP1A2CYP3A4 | |
| SCHEMBL29102436 | 0.77 | CYP2A6 (0.47) | ALDH1A1 | |
| SCHEMBL29919659 | 0.77 | CYP2A6 (0.47) | ALDH1A1 | |
| SCHEMBL2314941 | 0.75 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL6838380 | 0.73 | KDM4E (0.68) | KDM4EALDH1A1CYP3A4PARP10MEN1 | |
| SCHEMBL3819303 | 0.73 | CYP2D6 (0.46) | KDM4EALDH1A1GAACYP3A4MEN1 | |
| Ethenzamide SCHEMBL27612766 | 0.72 | MAPT (0.68) | KDM4EGAACYP3A4IRAK4MEN1 | |
| Ethenzamide SCHEMBL25624 | 0.72 | MAPT (0.68) | KDM4EGAACYP3A4IRAK4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0789020-B1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5780628-A | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0789020-A1 | Process for producing dioxoquinazolines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-13 | — | — | EP | disclosed |