Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.67 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.49 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | POLA1 | P09884 | 1/20 | 0.47 |
| ▸ | POLG | P54098 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | AHCY | P23526 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | RNASEL | Q05823 | 3/20 | 0.44 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2352757 | 0.81 | FGFR1 (0.86) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL29365535 | 0.81 | FGFR1 (1.00) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL49373 | 0.81 | FGFR1 (1.00) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| SCHEMBL8717563 | 0.80 | FGFR1 (0.84) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL28511793 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL3643715 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL28765885 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL3639260 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL439995 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 | |
| Adefovir SCHEMBL29115272 | 0.80 | FGFR1 (0.97) | FGFR1SLC22A6CYP3A4ADCY5ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999045016-A9 | NOVEL PRODRUGS FOR PHOSPHORUS-CONTAINING COMPOUNDS | METABASIS THERAPEUTICS INC (US) | 2000-03-02 | — | — | WO | disclosed |